Salmon Pasta Casserole- anti-cancer recipes- cook for your life

Salmon Pasta Casserole

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Clock Icon for Prep Time 30 min prep
Person Icon for Serving Size 6 servings
Carrot Icon for Number of Ingredients Size 10 ingredients
Ideal for any event, this Salmon Pasta Casserole is a great crowd pleaser. Classically delicious, the salmon adds a delightful twist of flavor, not to mention a nice boost of protein and surprising source...


  • 1 pound whole wheat penne pasta
  • 4 tablespoons butter
  • ½ cup minced onion
  • 2 tablespoons flour
  • 2 cups low-fat milk
  • 2 tablespoons lemon juice
  • 2 tablespoons chopped parsley
  • salt to taste
  • 8 ounces canned salmon, drained, flaked, skin and bones removed
  • 1 ½ cups shredded sharp cheddar cheese

Nutrition Facts


540 cals


19 g

Saturated Fat

10 g

Polyunsaturated Fat

2 g

Monounsaturated Fat

5 g


65 g


7 g


3 g


27 g


578 mg


  1. Cook pasta until just al dente according to package instructions.
  2. To make the sauce, melt the butter in a medium saucepot. Add the onion and sauté until transparent. Add the flour, and stir until combined. Cook for one minute or until the flour turns a light brown.
  3. Slowly stir in the milk. Cook, stirring constantly, until smooth and thick. The mixture should coat the back of a wooden spoon. Add lemon juice, parsley and season with salt.
  4. Spoon pasta into a greased casserole dish. Spread the salmon evenly over the top. Pour on third of the sauce over the pasta and salmon. Sprinkle 3/4 cup of cheese over it. Pour the rest of the sauce over it, and sprinkle with the remaining cheese.
  5. Bake at 375 for 25 minutes, or until hot and lightly browned.

Registered Dietitian Approved

All our recipes are created by chefs and reviewed by our oncology-trained staff Registered Dietitian, Kate Ueland, MS, RD, to ensure that each is backed with scientific evidence and meets the standards set by the Academy of Nutrition and Dietetics.

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