Salmon Pasta Casserole- anti-cancer recipes- cook for your life

Salmon Pasta Casserole

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Clock Icon for Prep Time 30 min prep
Person Icon for Serving Size 6 servings
Carrot Icon for Number of Ingredients Size 10 ingredients

Ideal for any event, this Salmon Pasta Casserole is a great crowd pleaser. Classically delicious, the salmon adds a delightful twist of flavor, not to mention a nice boost of protein and surprising source...


  • 1 pound whole wheat penne pasta
  • 4 tablespoons butter
  • ½ cup minced onion
  • 2 tablespoons flour
  • 2 cups low-fat milk
  • 2 tablespoons lemon juice
  • 2 tablespoons chopped parsley
  • Salt to taste
  • 8 ounces canned salmon, drained, flaked, skin and bones removed
  • 1 ½ cups shredded sharp cheddar cheese

Nutrition Facts


540 cals


19 g

Saturated Fat

10 g

Polyunsaturated Fat

2 g

Monounsaturated Fat

5 g


65 g


7 g


3 g


27 g


578 mg


  1. Cook pasta until just al dente according to package instructions.
  2. To make the sauce, melt the butter in a medium saucepot. Add the onion and sauté until transparent. Add the flour, and stir until combined. Cook for one minute or until the flour turns a light brown.
  3. Slowly stir in the milk. Cook, stirring constantly, until smooth and thick. The mixture should coat the back of a wooden spoon. Add lemon juice, parsley and season with salt.
  4. Spoon pasta into a greased casserole dish. Spread the salmon evenly over the top. Pour on third of the sauce over the pasta and salmon. Sprinkle 3/4 cup of cheese over it. Pour the rest of the sauce over it, and sprinkle with the remaining cheese.
  5. Bake at 375°F for 25 minutes, or until hot and lightly browned.

Registered Dietitian Approved

All our recipes are created by chefs and reviewed by our oncology-trained staff Registered Dietitian, Kate Ueland, MS, RD, to ensure that each is backed with scientific evidence and meets the standards set by the Academy of Nutrition and Dietetics.

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